FindTrial
Sign In

Eccentric exercise along with multimodal intervention in knee osteoarthritis

Eccentric exercise added to multimodal intervention improves pain, muscle strength, and function more than multimodal intervention alone in people with knee osteoarthritis: a randomised trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083675
Enrollment
120
Registered
2025-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Group A Eccentric + Multimodal Intervention: Participants in Group A will receive a multimodal intervention alone over six weeks, with three sessions per week (total of 18 sessions).

Sponsors

Kazi Md Azman Hossain
Lead Sponsor
Jashore University of Science and Technology JUST
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Individuals will be included in this trial if (1) ages 45 70 for both men and women; (2) the presence of unilateral knee OA for at least six months following American College of Rheumatology criteria; (3) able to walk without the use of any aids and able to flex the knee beyond 90 degrees; (4) anterior-posterior bilateral standing radiograph presents Kellgren and Lawrence Grade II/III knee OA; (5) (5) absence any unusual cardiac response during the six-minute walk test

Exclusion criteria

Exclusion criteria: Individuals will be excluded if (1) knee surgery has been performed in the previous twelve months; (2) lumbar radiculopathy, vascular claudication, severe anterior-sided knee pain resulting from patella-femoral syndrome or chondromalacia, as well as further neurological, muscular, or joint conditions that could impair the function of the lower limbs; (3) visible malformation of the knee, either varus or valgus; (4) received hyaluronic acid or corticosteroid injections within three months of study enrollment; (5) pregnancy; (6) BMI over 30

Design outcomes

Primary

MeasureTime frame
Pain (Numeric Pain Rating Scale), Pressure Pain Threshold (Algometer), Muscle strength (Sphygmomanometer), Function (WOMAC)Timepoint: Baseline, 6 weeks and 30 weeks—

Secondary

MeasureTime frame
Range of Motion (Goniometer), Aerobic capacity (6MWT), Depression (PHQ-9)Timepoint: At baseline, posttest after 6 weeks and follow-up after 24 weeks—

Countries

Bangladesh

Contacts

Public ContactAbid Hasan Khan

Jashore University of Science and Technology (JUST), Jashore

azmanhossain51@gmail.com01660140833

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026