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A Comparative Study Of Dexmedetomidine And Labetalol For Attenuation of Haemodynamic Stress Response to Laryngoscopy and Intubation

A Comparative Study Of Dexmedetomidine And Labetalol For Attenuation of Haemodynamic Stress Response to Laryngoscopy and Intubation: A Randomized Clinical Trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083669
Enrollment
102
Registered
2025-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj Dexmedetomidine 1mcg/kg: Study participants will receive inj Dexmedetomidine 1mcg/kg in 10ml normal saline i.v over 10 mins, 5 minutes before induction of anaesthesia. Control Inter

Sponsors

Pranesh Gurung
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient of either sex Patient with ASA physical grade 1 and 2

Exclusion criteria

Exclusion criteria: Patient refusal Difficult airway Uncontrolled Hypertension Uncontrolled Diabetes Mellitus Ischemic heart disease Severe Renal disease Cerebrovascular disease Patient on beta blockers, alpha blockers Bronchial Asthma Allergy to study drugs

Design outcomes

Primary

MeasureTime frame
Haemodynamic changes ( hypertension, tachycardia, hypotension, bradycardia) during laryngoscopy and intubation.Timepoint: Haemodynamic changes ( hypertension, tachycardia, hypotension, bradycardia) before starting infusion, 1 min after infusion, 1 min after induction, 1, 3 5, 15, 30 mins after intubation.—

Secondary

MeasureTime frame
Haemodynamic changes ( hypotension, bradycardia) during laryngoscopy and intubation.Timepoint: Haemodynamic changes ( hypotension, bradycardia) before starting infusion, 1 min after infusion, 1 min after induction, 1, 3 5, 15, 30 mins after intubation.—

Countries

India

Contacts

Public ContactN Anita Devi

Regional Institute Of Medical Sciences Imphal

dranitadevin@gmail.com8787458045

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026