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HES for propofol pain injection

Assessment of Efficacy of 6 percent Hydroxy Ethyl Starch pre-administration to alleviate pain on propofol injection- A randomized placebo-control study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083650
Enrollment
84
Registered
2025-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 6% Hydroxy ethyl starch: 50 ml of 6% hydroxy ethyl starch will be given intravenously before giving propofol. Control Intervention1: 0.9% Normal Saline: 50 ml 0.9% Normal saline will

Sponsors

Smt B.K.Shah Medical Institute and Research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient willing to sign the written& informed consent, patients aged between 18 to 60 years belonging to either gender posted for elective surgery under general anaesthesia, patients belonging to American Society of anesthesiologists grade I and II

Exclusion criteria

Exclusion criteria: Patient s refusal from taking part in the study, emergency surgery, patients having history of allergic reaction to propofol or HES, patients with sever cardiorespiratory compromise, diabetes, , raised creatinine level; patients in whom hands or forearm veins are not accessible.

Design outcomes

Primary

MeasureTime frame
to assess effectiveness of Hydroxy Ethyl starch for reduction of pain on propofol injection.Timepoint: 10 seconds after giving propofol

Secondary

MeasureTime frame
1. Asses severity of pain on propofol injection 2. Asses incidence of pain on propofol injection 3. Asses changes in Heart rate (HR) after Propofol Injection 4. Asses changes in Mean Arterial Pressure (MAP) after Propofol Injection Timepoint: 10 seconds after propofol injection

Countries

India

Contacts

Public ContactDr Jigisha Mehta

Smt B.K. Shah Medical Institute and Research Center, Sumandeep Vidyapeeth deemed to be university,

jbmehta.28@gmail.com08866718168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026