A comparison on a scoring system obtained with transesophageal echocardiography with central venosus pressure and pulse pressure variation during cardiac valve surgery to guide fluid management : an interventional study

A comparison of intraoperative VExUS score with central venous pressure and pulse pressure variation in guiding fluid management in patients undergoing valvular cardiac surgery: an interventional study - Nil

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083644

Enrollment

Registered

2025-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I080- Rheumatic disorders of both mitraland aortic valves

Interventions

Intervention1: Administring fluids intraoperatively based on VExUS score: VExUS score assessed intraoperatively will be used to decide up on fluid administration. Lower VExUS scores allow more fluid a

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to both genders of age group 18 to 65 years, NYHA grade one and two, Posted for elective single valve replacement i.e. Aortic or Mitral Valve replacement, Signed informed consent given by the patient

Exclusion criteria

Exclusion criteria: Patient refusal Double valve replacement patients Redo surgery Diagnosed heart failure patients. Patients contraindicated for esophageal echocardiography

Design outcomes

Primary

Measure	Time frame
To determine that VExUS score is superior to pulse pressure variation and central venous pressure in determining fluid status intraoperatively.Timepoint: The outcome will be assessed on the day of surgery in one day	—

Secondary

Measure	Time frame
1. Improvement in fluid management & fluid homeostasis. 2. Prevents multi organ fluid congestion. 3. Improved surgical outcome. 4. Reduces morbidity & mortality. Timepoint: All outcomes will be assessed on the day of surgery, in a single day	—

Countries

India

Contacts

Public ContactSHAREK

AIIMS Raipur

subratsing@gmail.com8518881767

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026