Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
None listed
Sponsors
SIUSRP Symbiosis International University Student Research Project seed funding
Eligibility
Inclusion criteria
Inclusion criteria: The inclusion criteria will be as follows: 1. Diagnosis of PCOS [Hrishikesh M, Madhuri P, Laxmi P, Advisors S, Gupte S, Divakar H, et al. FOGSI-ICOG Good Clinical Practice Recommendations GCPR on Update in Managing PCOS in Women. 2024.] In adult women, the diagnosis of PCOS will be made using the Rotterdam criteria, meeting two of the following three conditions: (Grade A, EL 4) i) Androgen Excess [ Biochemical: serum total testosterone Clinical: persistent acne, Hirsutism, female pattern baldness] ii) Ovulatory dysfunction( Oligo or anovulatory cycles) iii) Polycystic Ovarian morphology on Ultrasonography 2. Presentation of acanthosis nigricans with or without obesity is an additional diagnostic criterion for PCOS in adults and adolescents (Grade B, EL 4). 3. Mild prolactinemia and subclinical hypothyroidism are common in PCOS; prolactin, TSH levels will also be taken in consideration (Grade B, EL 4)[22] 4. Age 20 to 25 years old. 5. Willingness to wait till the study duration and then commence any allopathic treatment of PCOS/PCOD. 6. Willingness to provide written Informed consent.
Exclusion criteria
Exclusion criteria: 1. Menopause 2. Thyroid disorders 3. Use of hormonal medications for treating menstrual abnormalities over the previous three months. 4. Hyperlipidemia [high-density lipoprotein (HDL) < 50 mg/dL (1.3 mmol/L), low-density lipoprotein (LDL) > 100 mg/dl, and triglycerides (TG) > 150 mg/dl, total cholesterol (TC) > 240 mg/dL(6.21 mmol/L)] 5. Hyperprolactinemia 6. Diabetes 7. Alterations in physical activity levels over the past 6 months 8. Presently on any medications, including antihyperglycemic agents, lipid-lowering medications, contraceptives, corticosteroids, or any other supplements. 9. Pregnant and lactating women. 10. History of allergic reactions to Mangifera indica.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study shall provide an insight into the effectiveness of Mangifera indica leaves in the management and treatment of PCOS/PCOD, which shall pave the way for an alternative or adjunctive treatment to standardized management. There is a possibility of an assurance of new, cheaper, and efficient treatment modalities to be redefined in women afflicted with this endocrine and complication-involving disorder.Timepoint: 8 week intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| It will provide a framework for future studies on herbal intervention in the management of PCOS/PCOD. Timepoint: 8 weeks | — |
Countries
India
Contacts
Public ContactDr Kalyani Mahajan
Symbiosis medical college for women
Outcome results
None listed