Health Condition 1: - Health Condition 2: I083- Combined rheumatic disorders of mitral, aortic and tricuspid valves
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged above 18 year identified with isolated, severe native valve stenosis/regurgitation with or without concomitant moderate stenosis/regurgitant lesion with or without symptoms, preserved or reduced LVEF (LVEF more or less than 50%) planned for valve replacement as per ACC/AHA 2020 guidelines
Exclusion criteria
Exclusion criteria: 1.Patients with sub valvar / supravalvular lesions 2.Patients with valve prosthesis undergoing re-do surgery. 3.Patients implanted with permanent pacemaker. 4.Co-existing pulmonary artery disease of non-cardiac origin. 5.Patients diagnosed with coronary artery disease and concomitant valve disease scheduled for bypass surgery and valve replacement. 6.Patients having poor acoustic image quality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myocardial deformation parameters: Global longitudinal strain (%), 3D auto RV function, 3D chamber volumes Quality of life (WHO BREF score) Functional Activity assessment (DASI score)Timepoint: 3 time points At baseline, pre discharge and 6 month follow up | — |
Secondary
| Measure | Time frame |
|---|---|
| MACE Non Cardiovascular Mortality Surgical outcomes Echocardiographic & deformation parametersTimepoint: The outcomes will be assessed at 3 time points Baseline pre-discharge & at 6 months | — |
Countries
India
Contacts
Public ContactChaithra Nayak
Department of Cardiology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, 576104, India
Outcome results
None listed