Comparative Efficacy of Azithromycin Gel vs. Tetracycline Fibers in Diabetic Patients with Generalized Periodontitis Stage 3: A Randomized Controlled Study

Comparative Efficacy of 0.5 percent Azithromycin Gel with Tetracycline Fibers in the Treatment of Generalized Periodontitis Stage 3 in Diabetic Patients: A Randomized Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/03/083609

Enrollment

Registered

2025-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: 0.5% Azithromycin Gel: Local Drug Delivery of 0.5% Azithromycin Gel Once After Scaling and Root Planing for a Duration of 3 Months Control Intervention1: Tetracycline Fibers 2mg: Local

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age between 30 to 60 years. 2.Patients with diabetes ( HbA1c range = 6.5-8.5 ) 3.Subjects with minimum 20 natural teeth remaining. 4.Subjects having Stage III periodontitis

Exclusion criteria

Exclusion criteria: 1.Subjects consuming any form of tobacco. 2.Pregnant and lactating women. 3. Having symptoms of acute illness or pulpal pain at the time of the study. 4. Systemically healthy patients 5. patients having allergy to either tetracycline or azithromycin .

Design outcomes

Primary

Measure	Time frame
Clinical attachment loss, Probing depth, Gingival marginal position and Hba1c variablesTimepoint: baseline , 1 month and 3 months	—

Secondary

Measure	Time frame
modified sulcular bleeding index , plaque indexTimepoint: baseline , 1 month & 3 month	—

Countries

India

Contacts

Public ContactDr Kaustubh Ainapure

K.M Shah Dental College and Hospital , Sumandeep Vidyapeeth .

drprasadnadig@gmail.com8469779161

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026