Comparison of intravenous Acetaminophen, ketorolac and ibuprofen for the post operative analgesia after urological surgeries

A comparative evaluation of intravenous Acetaminophen, ketorolac and ibuprofen for the post operative analgesia in the patients undergoing urological surgeries under balanced general anaesthesia- A randomised controlled trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/03/083605

Enrollment

Registered

2025-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N22- Calculus of urinary tract in diseases classified elsewhere

Interventions

Intervention1: Injection ibuprofen: Ibuprofen iv formulations are yet to be explored.uptil now Ibuprofen has been used in various oral formulations but the iv formulations are supposed to be revolutio

Eligibility

Inclusion criteria

Inclusion criteria: 1) All Urological surgeries like RIRS , PCNL, Nephrectomy, ESWL etc 2) Under Balanced General Anaesthesia

Exclusion criteria

Exclusion criteria: 1)ASA grade - III/IV 2) Patients undergoing urological surgeries under spinal or epidural or sedation anaesthesia

Design outcomes

Primary

Measure	Time frame
To find out the effect on post operative analgesia on administration of Inj Acetaminophen/ Ketorolac or Ibuprofen given intravenously in patients undergoing urological surgeries under Balanced General Anaesthesia .Timepoint: T0- Before Induction T1- Immediately after shifting to post- operative recovery room(RR) T2- After giving analgesia of assigned group. T3- Every 15 mins for 2 hours in RR. T4- Every 4 hours till 24 hours stay at the hospital.	—

Measure

Time frame

To find out the effect on post operative analgesia on administration of Inj Acetaminophen/ Ketorolac or Ibuprofen given intravenously in patients undergoing urological surgeries under Balanced General Anaesthesia .Timepoint: T0- Before Induction T1- Immediately after shifting to post- operative recovery room(RR) T2- After giving analgesia of assigned group. T3- Every 15 mins for 2 hours in RR. T4- Every 4 hours till 24 hours stay at the hospital.

—

Secondary

Measure	Time frame
To find out if any hemodynamic changes or side effects occur on administration of Intravenous Acetaminophen /Ketorolac or Ibuprofen in patients undergoing urological surgeries under Balanced General Anaesthesia.Timepoint: T0- Before Induction T1- Immediately after shifting to post- operative recovery room. T2- After giving analgesia of assigned group.	—

Countries

India

Contacts

Public ContactDr MRIDUL M PANDITRAO

AIMSR, bathinda

drmmprao1@gmail.com8699921884

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026