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Comparison of pain relief and infection control with negative pressure versus passive ultrasonic cleaning in the treatment of tooth infection- a randomized clinical study

Comparative evaluation of post-operative pain and antimicrobial efficacy of negative pressure versus passive ultrasonic irrigation activation in symptomatic apical periodontitis - A randomized clinical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083601
Enrollment
48
Registered
2025-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Negative pressure irrigation activation (Pulp Sucker system): root canal irrigation will be performed using the pulp sucker system and antimicrobial load will be assessed after access o

Sponsors

Dr Vivek Hegde
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with chronic irreversible pulpitis with symptomatic apical periodontitis indicated for endodontic treatment PAI score or Periapical Index Score less than or equal to 3 (Dag Orstavik) Mandibular Premolars with a single root and a single canal Patients having no significant systemic conditions Patients who are ready to give written informed consent

Exclusion criteria

Exclusion criteria: Teeth with sinus drainage Fractured tooth Teeth with root resorption Non restorable and periodontally compromised teeth Re-treatment cases Patients who received analgesics or antibiotics within the preceding 12 hours before the procedure Pregnant and lactating women Patients having severe malocclusion associated with a traumatic occlusion Teeth with calcified canals Teeth with an open apex

Design outcomes

Primary

MeasureTime frame
To evaluate and compare antimicrobial efficacy following irrigation activation using Pulpsucker system, XP Endo finisher, Manual dynamic agitation and Conventional needle during root canal therapyTimepoint: baseline and after final irrigation on first appointment

Secondary

MeasureTime frame
To evaluate and compare post-operative pain following irrigation activation using Pulpsucker system, XP Endo finisher, Manual dynamic agitation and Conventional needle during root canal therapyTimepoint: 24 hours. 48 hours. 72 hours.

Countries

India

Contacts

Public ContactDr Kunal Bagade

M A Rangoonwala Dental College and Hospital

bagade.kunal111@gmail.com7843060996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026