A study which compares the effect of spinal anesthesia drug in human body when given as bolus and when given as fractions in patients undergoing planned cesarean section

Comparison of fractionated dose versus bolus dose injection in spinal anaesthesia for patients undergoing elective caesarean section - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083531

Enrollment

Registered

2025-03-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A - Bolus dose: Patients who are undergoing elective cesarean section will receive a single bolus dose of levobupivacaine with buprenorphine intrathecally over 10 seconds and will

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status I and II, age from 18 to 40 years, height from 150 to 170 cm, pregnancies scheduled for elective Lower Segment Caesarean Section under Spinal anaesthesia

Exclusion criteria

Exclusion criteria: Pre-existing diseases Pregnancy-induced hypertension Cardiovascular disease Cerebrovascular disease Any contraindication to Spinal anaesthesia Weight less than 50 kg or more than 110 kg Height less than 150 cm Severely altered mental status Spine deformities History of laminectomy

Design outcomes

Primary

Measure	Time frame
To compare the hemodynamic stability in fractionated dose versus bolus dose in spinal Anaesthesia for patients undergoing elective lower segment caesarean section (LSCS). Timepoint: First 6 hours	—

Secondary

Measure	Time frame
To compare duration of analgesia and to compare the sensory and motor block characteristics Timepoint: First 6 hours	—

Countries

India

Contacts

Public ContactDr Anand S

Chettinad Hospital and Research Institute

dranandmurugan@gmail.com9444486183

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026