Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene
Conditions
Interventions
Intervention1: Injection GLYCOPYRROLATE O.2 milligrams Intravenous: Administration of prophylactic intravenous injection GLYCOPYRROLATE
(0.2 mg) diluted with sterile water to 0.04mg/cc in a 5 ml clear
Sponsors
Kodagu Institute of medical sciences and teaching hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Elective unilateral inguinal hernioplasty surgeries under spinal anaesthesia 2.American Society of Anaesthesiologists Grade I and Grade II of male/female gender. 3.Patients aged between 18 to 60 years. 4.Patients with BMI less than 30 kg/m2. 5.Patients with height between 155 -170 centimeters
Exclusion criteria
Exclusion criteria: 1. Patients on Beta blockers, Calcium channel blockers, and alpha 2 agonists 2. Gross spinal abnormality. 3. Infection at the site of lumbar puncture. 4. Pre-existing Hemorrhagic diathesis. 5. Pre-existing Neurological disorders. 6. History of allergy to the study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure the effectiveness of pre emptive intravenous ondansetron and glycopyrrolate in prevention of spinal hypotension by measuring the Mean Arterial Pressure(MAP) to assess the incidence and severity of hypotension after administration of spinal anesthesiaTimepoint: Every 2 min for first 20 min Every 5 min thereafter till end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the total vasopressor requirement after administration of spinal anaesthesiaTimepoint: Number of doses of vasopressor drugs given intraoperatively after the administration of spinal anesthesia till the end of surgery | — |
Countries
India
Contacts
Public ContactDr Aiyappa D S
Kodagu Institute of medical sciences
Outcome results
None listed