Which Numbing Medicine Works Better for Kids Dental Procedures: Buffered Articaine or Mepivacaine?

Comparative evaluation of clinical performance buffered articaine versus mepivacaine An IN VIVO Study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083508

Enrollment

Registered

2025-03-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Buffered Articaine: Articaine will be buffered with sodium bicarbonate to optimize its pH to normal and compared against plain mepivacaine as a local anesthetic agent in pediatric denta

Eligibility

Inclusion criteria

Inclusion criteria: Pediatric population, Co-operative patients (Frankel s III or IV),Patients in need of exodontia, Patients in need of pulp therapy

Exclusion criteria

Exclusion criteria: Children suffering from any systemic disease, Children under any kind of medication, Highly uncooperative children (Frankel s I or II), With known history of LA allergy.

Design outcomes

Primary

Measure	Time frame
Faster Onset of action Eliminates the need of repeated nerve injections Longer duration of action Timepoint: Base line	—

Secondary

Measure	Time frame
Pleasant Dental Visit Behavior modificationTimepoint: 1 week	—

Countries

India

Contacts

Public ContactDr Kapil Dev Gupta

Teerthanker Mahaveer Dental College and Research centre

drkarthikbaskar@gmail.com07358234404

Outcome results