Health Condition 1: C679- Malignant neoplasm of bladder, unspecified
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Chittaranjan National Cancer Institute
Eligibility
Inclusion criteria
Inclusion criteria: Patients diagnosed with muscle-invasive bladder cancer (MIBC, cT2-T4aN0M0), eligible for both bladder preservation and radical cystectomy and giving informed consent to participate
Exclusion criteria
Exclusion criteria: Patients with metastatic disease (M1) at presentation or having received prior pelvic irradiation or surgery affecting urinary/bowel function or patients unwilling to complete PROM questionnaires
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare quality of life (QoL) outcomes between bladder preservation and radical cystectomy patients using validated PROM tools namely Bladder Cancer Index (BCI) & EORTC QLQ-C30 Timepoint: At 3 months, 6 months, 9 months, 12 months and thereafter annually all relevant follow up data and filled PROM questionnaires shall be collected, till completion of this study. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess overall survival (OS) and progression-free survival (PFS) of patients undergoing bladder preservation versus radical cystectomy & to correlate PROM-derived QoL scores with survival outcomes.Timepoint: At 3 months, 6 months, 9 months, 12 months and thereafter annually all relevant follow up data and filled PROM questionnaires shall be collected, till completion of this study. | — |
Countries
India
Contacts
Public ContactDr Debjit Ghosh
Chittaranjan National Cancer Institute
Outcome results
None listed