Vitamin D Supplementation in the Management of Essential Hypertension Among Patients with Vitamin D Deficiency

Vitamin D Supplementation Versus Standard Treatment in the Management of Essential Hypertension Among Patients with Vitamin D Deficiency: A Randomised Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083498

Enrollment

280

Registered

2025-03-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension

Interventions

Intervention1: vitamin D supplementation plus Telmisartan: Tab Vit D 60,000IU once a week plus Telmisartan 40 mg twice a day for 8 weeks Control Intervention1: Telmisartan plus Placebebo: Telmisartan

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adults aged 18 years and older. 2.Confirmed diagnosis of essential hypertension (systolic BP greater than 130 mm Hg and/or diastolic BP than 80 mm Hg) based on standard guidelines. 3.Serum 25-hydroxyvitamin D levels between 20 to30 ng/mL (50 to75 nmol/L). 4.Willingness to provide informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Secondary Hypertension: History of secondary causes of hypertension (e.g., renal artery stenosis, endocrine disorders). 2. Presence of severe cardiovascular, liver, or renal disease that may interfere with study outcomes. 3.Recent use of vitamin D supplements (within the last 3 months) or other medications affecting blood pressure. 4.Serum 25-hydroxyvitamin D levels below 20 ng/mL (50 nmol/L). 5.Pregnant or breastfeeding women.

Design outcomes

Primary

Measure	Time frame
Blood Pressure Reduction: Changes in systolic and diastolic blood pressure measurements from baseline to the end of the studyTimepoint: 8 weeks	—

Secondary

Measure	Time frame
Serum 25-Hydroxyvitamin D Levels: Changes in serum vitamin D levels before and after supplementation.Timepoint: 8 weeks;SF=36 Scale - Quality of Life QuestionnaireTimepoint: 8 weeks	—

Countries

India

Contacts

Public ContactPrathmesh Sandesh Deolekar

Meenakshi Medical College Hospitals and Research Institute

galusrinivasan@gmail.com9600754423

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026