Health Condition 1: G819- Hemiplegia, unspecified Health Condition 2: G909- Disorder of the autonomic nervoussystem, unspecified Health Condition 3: G94- Other disorders of brain in diseases classified elsewhere Health Condition 4: G939- Disorder of brain, unspecified Health Condition 5: G988- Other disorders of nervous system
Conditions
Interventions
Intervention1: Ferment rice water (Torani) and xylitol mixture: The bottles shall be packed with 350 ml of the Torani and 5 gm of Xylitol added to the bottle and sealed and capped. The study IDs of th
Sponsors
Dr Basanti Kumari Pathi
Dr Manoja Kumar Das
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient admitted within last 48 hours. 2. Patient anticipated to be admitted for at least 7 days. 3. Patient who will be allowed oral intake or Ryle’s tube feeding. 4. patient who will give informed consent.
Exclusion criteria
Exclusion criteria: 1. Patient who is not allowed orally or on nil per-oral advise. 2. Patient with known immunocompromised condition (requiring immune-suppressants, on long term high dose oral/parenteral steroids or on chemotherapy/radiotherapy). 3. Patient who is scheduled for intestinalor abdominal surgery. 4. Patient who is admitted for only diagnostic test and short term assessment. 5. Patient who is sick enough with unstable vitals and/or requiring life-support medications/measures. 6. Patient who will have renal failure or on fluid restriction. 7. Patient with known food allergy or xylitol intolerant. 8. Patient who is not expeceted to comply with the trial protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Clostridium difficile infection or colonization statusTimepoint: 15 days. | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. Clostridium difficile infection or colonization at discharge from hospital 3. Clostridium difficile infection or colonization after three months 4. Characterize the phenotype and genotype of the Clostridium difficile isolated 5. The illness episodes, antibiotics usage and outcome through three months after discharge (at 30, 60 and 90 days). 6. The tolerance and safety of the Torani-xylitol mix in these elderly patients.Timepoint: at discharge, 30 days, 60 days, and 90 days. | — |
Countries
India
Contacts
Public ContactDr Basanti Kumari Pathi
Kalinga Institute of Medical Sciences
Outcome results
None listed