Health Condition 1: A30- Leprosy [Hansens disease]
Conditions
Interventions
Intervention1: polymerase chain reaction: polymerase chain reaction of a skin biopsy is done which has good sensitivity and specificity
Intervention2: Auramine-O: slit skin smear sample for ear lobe
Sponsors
Shri Ram Murti Smarak Institue of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Clinically diagnosed patients of leprosy as per the consensus of two qualified dermatologists working in the department.
Exclusion criteria
Exclusion criteria: Patient/ guardians of patients unwilling to give written informed consent with photography. Hypersensitivity to local anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In a study by Girma S, Avanzi C, Bobosha K, Desta K, Idriss MH, Busso P, et al, Auramine-O was considered a user friendly method and good for peripheral centers where trained staff is available with difficulty. It also showed that Auramine-O has better sensitivity than ZN staining as it was easier to read. Whereas PCR was considered good for urban centers where there is no shortage of resources in terms of money and trained manpower.Timepoint: baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| result of Auramine-O obtained in 1 day can help in starting the treatment earlyTimepoint: 1 day | — |
Countries
India
Contacts
Public ContactTanya Gupta
Shri Ram Murti Smarak Institute of Medical Sciences
Outcome results
None listed