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A study to compare the effect of transdermal buprenorphine and transdermal diclofenac patch for post operative pain relief in major surgeries.

A comparative study of analgesic efficacy between transdermal buprenorphin patch and transdermal diclofenac patch for post operative pain relief in major surgeries - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083412
Enrollment
62
Registered
2025-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Application of trans-dermal Patch: Trans-dermal Patches will be applied on lateral aspect of left arm preoperatively and will be kept for 24 hours after complete recovery from general o

Sponsors

Bharat Ratna Late Shri Atal Bihari Vajpayee Memorial Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age group: 18-60 years Patients posted for elective major surgeries under general anesthesia or spinal anesthesia with ASA-1 or ASA-2 grade

Exclusion criteria

Exclusion criteria: .Patients refusal .Pregnant and lactating women .Age more than 60 years .ASA grading more than or equal to 3 .History of allergy to Buprenorphine, Diclofenac, Paracetamol .Opioid Dependents .Cardiac, kidney, Liver disease and coagulation disorders .Patients with pain due to cause other than presenting illness

Design outcomes

Primary

MeasureTime frame
.Visual analog scale after complete recovery from general or spinal anaesthesia in group with Buprenorphine patch. .Visual analog scale after complete recovery from general or spinal anaesthesia in group with Diclofenac patch.Timepoint: 0, 2nd, 4th, 8th, 12th, 24 hour after complete recovery from general or spinal anaesthesia in group with Buprenorphine patch and Diclofenac patch.

Secondary

MeasureTime frame
.Total rescue analgesia required in group with Buprenorphine patch and diclofenac patch .Comperision of sode effects and complication in group with Buprenorphine patch and Diclofenece patch.Timepoint: 0,2nd,4th,8th,12th,24hour after complete recovery from general or spinal anaesthesia patch and diclofenac patch

Countries

India

Contacts

Public ContactDr Durga Kashyap Kosam

Bharat Ratna Late Shri Atal Bihari Vajpayee Memorial Medical College, Rajnandgaon

Kosamdurga@gmail.com9826075062

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026