To compare the effect of carbon dioxide insufflation at different rates on hemodynamic parameters during laparoscopic surgery

A randomised controlled trial to compare the effect of carbon dioxide insufflation at different rates on hemodynamic parameters during laparoscopic surgery - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083408

Enrollment

120

Registered

2025-03-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K806- Calculus of gallbladder and bile duct with cholecystitis

Interventions

Intervention1: Carbon dioxide insufflation at different rates during laparoscopic surgery: Compare the effect of different carbon dioxide insufflation at 1L/min, 3L/min and 5L/min on hemodynamic param

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologist (ASA) classification I-II. 2. 18-60 years old patients undergoing elective laparoscopic surgery willing to participate in study.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Patients for emergency laparoscopy. 3. Hypertensive patients. 4. Patients receiving sympathomimetic/sympatholytic medications

Design outcomes

Primary

Measure	Time frame
1. Mean arterial pressure immediately after achieving target intra-abdominal pressure (T2). 2. Heart rate immediately after achieving target intra-abdominal pressure (T2).Timepoint: every 2 minutes upto 10 minutes after attainment of target pressure	—

Secondary

Measure	Time frame
Shoulder pain one hour post-operatively using Visual Analog Scale (VAS) score.Timepoint: The shoulder pain will be assessed using the Visual Analog Scale (VAS), with 0 being no pain and 10 being the worst possible pain, after 1 hour of completion of surgery	—

Countries

India

Contacts

Public ContactDr Sanjeev Kumar

Maharaja Agrasen Medical College Agroha District Hisar

docsanjeevparmar77@gmail.com8059598861

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026