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Effectiveness of Light Therapy and Metformin Gel Along with Deep Cleaning for Treating Gum Disease: A Clinical Study

Clinical efficacy of Photodynamic therapy and 1% Metformin gel as an adjunct to scaling and root planing in the treatment of Periodontitis A randomized clinical trial - NSPT

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083402
Enrollment
25
Registered
2025-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Photodynamic therapy: Photodynamic therapy along with scaling and root planing was done to the patient 6 months Intervention2: 1% metformin gel: Patient is treated with 1%metformin gel

Sponsors

B Sai Prathyusha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients with sites showing probing depth 4-6 mm 2.No history of periodontal therapy or 3.use of antibiotics in the preceding 6 months.

Exclusion criteria

Exclusion criteria: 1.Patients with known systemic disease 2.Known or suspected allergy to Metformin [MF] 3.Patients on systemic MF or other oral antidiabetic therapy. 4.Patients with aggressive periodontitis 5.Use of tobacco in any form and alcoholism 6.Immunocompromised patients. 7.Pregnant or lactating females. 8.If the study reported additional treatments (e.g. Local or systemic antimicrobial therapy, adjunctive laser therapy, periodontal surgical therapy) other than SRP + aPDT.

Design outcomes

Primary

MeasureTime frame
Clinical attachment level Probing pocket depthTimepoint: baseline 3 months 6 months

Secondary

MeasureTime frame
Oral hygiene index Gingival index plaque index sulcular bleeding indexTimepoint: baseline 3 months 6 months

Countries

India

Contacts

Public ContactDr B SAI PRATHYUSHA

Sree sai dental college and research institute

anweshperio@gmail.com6303927456

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026