Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: GROUP KETODEX(KD) AND GROUP KETAMINE AND LIGNOCAINE (KL): Group KD (KETODEX): IV infusion of 1 mg/kg inj. Ketamine iv and 1mcg/kg inj.dexmedetomidine iv for 10 minute beforeinduction .
Sponsors
AIIMS BHOPAL
Eligibility
Inclusion criteria
Inclusion criteria: ina) 18 to 65 years, either gender. b) American Society of Anaesthesiologists physical status (ASA) I & II.
Exclusion criteria
Exclusion criteria: a) Patients refusing informed consent. b) Patients not extubated after surgery. c) Patients who are with the known allergic history to any of the study drugs. d) Patients who are pregnant e) Surgical duration more than 4 hours. f) Patients with known psychiatric illness g) Patients who are on treatment for chronic pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary: 1. To comparatively evaluate the visual analogue scale (VAS) score between the groups just after extubation, 2 hours ,4hours ,8 hours ,12hours and 24 hours. 2. To comparatively evaluate the emergence time and time taken to obtain the modified Aldrete score of 9 or more between the groups Timepoint: 0,2,4,6,12,24 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary: 1. To comparatively evaluate the mean arterial pressure (MAP) and heart rate (HR) between groups during the induction, intubation and immediately after prone position. 2. To comparatively evaluate the time point for the first ask of analgesic after extubation between the groups. 3. To comparatively evaluate the total requirement of rescue analgesia and perioperative total opioid consumption between the groups. 4. To comparatively evaluate the complications associated with infusions like bradycardia, hypotension, hypertension, sedation, nausea and vomiting in post operative period.Timepoint: 0,2,4,6,12,24 hrs | — |
Countries
India
Contacts
Public ContactDr Ashutosh Kaushal
All India Institute of Medical Sciences
Outcome results
None listed