Health Condition 1: K590- Constipation
Conditions
Interventions
Intervention1: Probiotic Lactobacillus sporogenes along with standard therapy of PEG: Children in the intervention arm will be given standard therapy of Polyethylene glycol at the dose of 1-1.75 gm/kg
Sponsors
Dr Samarendra Mahapatra
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 5-14 years with functional constipation defined according to Rome IV criteria Symptomatic for more than 4 weeks
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of bowel movements per week at the 4th week of treatment in intervention and control armsTimepoint: Baseline, 4th week | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of Stool microbiome analysis pre- treatment and at the 4th week of treatment in both the arms Timepoint: At beginning and at 4th week;Comparison of Stool consistency pre- treatment and at the 4th week of treatment in both the arms according to the Bristol Stoo Form ScaleTimepoint: At beginning and at 4th week;Comparison of adverse event between two groupsTimepoint: At 4th week | — |
Countries
India
Contacts
Public ContactDr Samarendra Mahapatra
AIIMS Bhubaneswar
Outcome results
None listed