Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Conditions
Interventions
Intervention1: Dexmedetomidine as anti-shivering agent post spinal Anaesthesia.: To determine the incidence of successful recovery from shivering in post spinal anaesthesia patients along with time ta
Sponsors
Department of Anaesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 65 years. 2. Physical status 1 and 2 according to American Society of Anaesthesiologists (ASA). 3. Have undergone spinal anaesthesia and having Grade 3 AND Grade 4 shivering post spinal anaesthesia. 4. Amount of fluid to be given is as co-loading 10ml/Kg bodyweight and as maintenance as per the need to maintain the hemodynamic status of the patient. 5. Duration of surgery not more than 120 minutes.
Exclusion criteria
Exclusion criteria: 1. Patients who are unwilling to participate. 2. Patients with significant cardiac, pulmonary, hepatic or renal diseases. 3. Abnormal coagulation profile. 4. Spinal deformities. 5. Evidences of skin infection at the site of injection. 6. Disabling neuropsychiatric disorder. 7. Known hypersensitivity to Dexmedetomidine. 8. Anticipated difficult intubation. 9. Chronic drug abusers and alcoholics. 10. Surgery converted to general anaesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Number of patients with complete response(shivering grade less than 2) 2. Efficacy of shivering control, assessed by the Time to cease shivering following the different doses of study drug administration and comparing them.Timepoint: 1. Number of patients with complete response(shivering grade less than 2) 2. Efficacy of shivering control, assessed by the Time to cease shivering following the different doses of study drug administration and comparing them. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Shivering scores between the different groups, recorded at various time intervals. 2. Compare the systolic blood pressure, diastolic blood pressure, heart rate at different intervals before & after drug administrations. 3. Ramsay sedation scale will be assessed in all patients at 0, 5, 15, 30, 60, 120 minutes post dosage. 4. Any adverse events like nausea, vomiting, palpitation, excessive sedation etc. will be recorded & compared between groups.Timepoint: 0 minutes, 5 minutes, 15 minutes, 30 minutes, 60 minutes, 120 minutes. | — |
Countries
India
Contacts
Public ContactDr Amit Kumar Ray
Institute of post graduate medical education and research
Outcome results
None listed