To study the effects of metformin therapy on insulin resistance and body composition in lean vs.obese PCOS patients

An open label, interventional controlled pre-post study of the effects of metformin therapy on insulin resistance and body composition in lean vs.obese PCOS patients - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083265

Enrollment

136

Registered

2025-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E282- Polycystic ovarian syndrome

Interventions

Intervention1: Drug therapy: Comparison of efficacy of 6 months of metformin therapy in lean vs obese PCOS patients Intervention2: Comparator: Lean vs obese PCOS patients Control Intervention1: Metfor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Phenotypic features of PCOS and fulfilling Rotterdam criteria 2. With written informed consent 3.not on any treatment for last 3 months

Exclusion criteria

Exclusion criteria: 1. Secondary causes of oligo-an ovulation 2.h/o intake of drugs in preceding 3 months 3. Pregnancy and lactation 4. Diabetes mellitus 5. Uncontrolled Hypertension 6.not giving consent

Design outcomes

Primary

Measure	Time frame
Change in insulin resistance indicesTimepoint: After 6 months	—

Secondary

Measure	Time frame
1. Change in body composition parameters 2.change in metabolic parameters 3.change in hormonal parameters 4.regularisation of menstrual cycle 5. Change in clinical signs of hyperandrogenismTimepoint: After 6 months	—

Countries

India

Contacts

Public ContactDr. Mona Sood

RNT Medical college, Udaipur

Drsandeepkansara@yahoo.co.in9352241126

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026