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Assessing the after surgical pain reduction by giving one lower dose of Gabapentin 100mg before varicose vein operation.

Effectiveness of a Single preoperative low dose of Gabapentin 100mg in reducing postoperative pain in varicose vein surgery. - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083257
Enrollment
60
Registered
2025-03-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I832- Varicose veins of lower extremities with both ulcer and inflammation

Interventions

Intervention1: Oral Gabapentine Suspension group: Oral Suspension Gabapentine 100mg Single dose 2hrs prior to surgery Control Intervention1: Placebo group: Oral Placebo drug is composition of Carboxym

Sponsors

Arul nirmal raj S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) All ASA 1 and 2 patients for varicose vein surgery b) Age between 18 to 60 years

Exclusion criteria

Exclusion criteria: a)Patient refusal b)ASA more than 3 patient c)Ideal body weight less than 50 kg d)Allergic to Gabapentin e)Patient on antiepileptics f)Contraindication to opioids and paracetamol

Design outcomes

Primary

MeasureTime frame
comparison of post operative pain in patients taking single pre op dose of gabapentin and preop placeboTimepoint: will be assessed at 4hrs after giving spinal anaesthesia then every 1hrs for first 24 hrs.

Secondary

MeasureTime frame
a.To measure the Sedation using Ramsay sedation scale in the postoperative period b.To calculate the total requirements of analgesia used in first 24 hours postoperatively. c.To measure the incidence of nausea and vomiting Timepoint: First 24 hrs of postop period

Countries

India

Contacts

Public ContactTony thomson chandy

christian medical college, vellore

tonythomson@cmcvellore.ac.in9500242412

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026