Comparing high versus low frequency rTMS for neuropathic pain in spinal cord injury patients

A study to compare efficacy of high versus low frequency rtMS on Dorsolateral prefrontal cortex in neuropathic pain management among patients with spinal cord injury : A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083241

Enrollment

Registered

2025-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M792- Neuralgia and neuritis, unspecified

Interventions

Intervention1: High Frequency rTMS : Magnetic stimulation will be provided using Neurosoft MS/MD stimulator with angulated figure of 8 coil. Each patient will receive stimulation once per day for 5 da

Eligibility

Inclusion criteria

Inclusion criteria: Admitted Spinal cord injury patients to PMR ward or OPD, both traumatic and non traumatic. Duration of injury at least 6 months from spinal cord injury. Patients diagnosed with neuropathic pain. Duration of injury of neuropathic pain more than 3 months. Patients who are capable of or willing to give informed consent.

Exclusion criteria

Exclusion criteria: Patients with any Intracranial metallic hardware such as electrodes, aneurysm clips or coils, stents and programmable ventriculoperitoneal shunts. Patients with Implanted electronic device: cochlear implants, vagus nerve stimulators, pacemakers or implantable cardioverter defibrillators and spinal cord stimulators. History of Vascular, traumatic, tumoral, Infectious brain lesion. Patients not willing to give informed consent. Patients with epilepsy or history of epilepsy. Patients with cognitive dysfunction who cannot cooperate. Patients not having preserved visible voluntary muscle twitch in any hand in thenar muscles Patients with unstable vital signs.

Design outcomes

Primary

Measure	Time frame
VAS scoreTimepoint: Pre and post intervention	—

Secondary

Measure	Time frame
H reflex Parameters (H wave amplitude & latency, M wave amplitude & latency, H/M ratio)Timepoint: Pre and Post intervention;Quality of life using ISCoS QoL data setTimepoint: Pre and Post intervention;SF-MPQ-2Timepoint: Pre and post intervention;AISTimepoint: Pre and post intervention;DASS- 21Timepoint: Pre and Post intervetnion;MASTimepoint: Pre and Post intervention	—

Countries

India

Contacts

Public ContactGita Handa

All India Institute of Medical Sciences, New Delhi

drgita.pmr@aiims.edu9899664489

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026