Health Condition 1: N040- Nephrotic syndrome with minor glomerular abnormality
Conditions
Interventions
Intervention1: Low dose steroid: Patient in intervention group will receive low dose (1.5 mg/kg/day) prednisolone till remission followed by 1.5mg/kg alternate day for two weeks and 1mg/kg alternate d
Sponsors
Aiims Bathinda
Aiims Bathinda
Eligibility
Inclusion criteria
Inclusion criteria: 1)Children aged between 2 to 13 years present to pediatric OPD or IPD with steroid sensitive nephrotic syndrome. 2)Those in relapse 3)Those patients who were not receiving prednisone at the time of relapse and had never before received other steroid sparing drugs.
Exclusion criteria
Exclusion criteria: 1)Steroid resistant and steroid dependent 2)Patient with nephrotic syndrome due to secondary causes. 3)Patients with frequent relapses 4)Patients in whom initial episode was not treated with at least 2 mg/kg of daily steroids for 4 weeks followed by 4 weeks of 1.5 mg/kg alternate day steroids during.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of relapses in steroid sensitive nephrotic syndrome on low dose prednisoloneTimepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Comparison of steroid toxicity in both the groups. 2)Difference in Linear growth with both the regimen Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactDr Raksha Ranjan
AIIMS Bathinda
Outcome results
None listed