Comparison of the effect of Atropine on Saliva Flow in Patients undergoing dental treatment

Comparative Evaluation of Reduction in Salivary Flow Rate by using Sublingual Atropine Sulphate Drops during Dental Treatment Procedure. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083225

Enrollment

Registered

2025-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Anticholinergic drug - atropine sulphate: atropine sulphate drops given sublingually by using dropper based on weight of the patient. given dose is 0.03mg/kg of body weight. Control Int

Eligibility

Inclusion criteria

Inclusion criteria: Patients without any systemic conditions. All participants will be at least 18 years old, if a female non-pregnant and non-breastfeeding, and normotensive with no signs of heart disease.

Exclusion criteria

Exclusion criteria: Patients with any systemic conditions patients with allergy to atropine patients with known kidney or liver impairment,anemic, treated with an anticholinergic medication

Design outcomes

Primary

Measure	Time frame
Reduction in Salivary Flow Rate during Dental Treatment Procedure.Timepoint: measurement of salivary flow at baseline,60 minutes and 90 minutes.	—

Secondary

Measure	Time frame
change in systemic blood pressure,diastolic blood pressure and heart rate are the secondary outcomes.Timepoint: time point are baseline ,60 minutes and 90 minutes.	—

Countries

India

Contacts

Public ContactDr Snehal Sunil Shinde

Jawahar Medical Foundations Annasaheb Chudaman Patil Memorial Dental College , Dhule.

dralishabwani@gmail.com8788919851

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026