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To compare the effect of anesthesia with anaesthetic gas sevoflurane versus isoflurane on blood sugar levels in brain cancer surgeries

Comparison of the effect of anesthesia with sevoflurane versus isoflurane on blood glucose trends in intracranial mass excision surgery - nil

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083071
Enrollment
90
Registered
2025-03-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Isoflurane: Isoflurane will be used as maintainence agent through inhalational route during general anaesthesia in a concentration so as to achieve minimal alveolar concentration of 0.

Sponsors

PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of any sex, non diabetic, ASA status I & II and posted for intracranial mass excision surgery under general anesthesia

Exclusion criteria

Exclusion criteria: The patients who are diabetic, have disorders of glucose metabolism, are pregnant and lactating , have renal, cardiovascular, pulmonary or hepatic disease, are chronic alcoholic, are taking insulin, oral hypoglycemic agents, antipsychotic drugs and beta adrenergic blocking drugs or are not willing to give consent

Design outcomes

Primary

MeasureTime frame
To note the baseline blood glucose level (before induction) and then the hourly change in intraoperative glucose levels with the use of sevoflurane or isoflurane as a maintenance inhalational agent.Timepoint: Before induction and every hour after induction till completion of surgery

Secondary

MeasureTime frame
To note the baseline heart rate, saturation and mean arterial blood pressure and intraoperatively every 2 hour after induction.Timepoint: Before induction and every two hour after induction till completion of surgery

Countries

India

Contacts

Public ContactDr Nitu Yadav

PGIMS Rohtak

ynitu29@gmail.com918708642484

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026