Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Administration of study drug/drugs: Patients who meet the criteria for the study will be divided into two groups using a computer generated random table and administered the study drug/
Sponsors
DrVanchula Srinivasan
DrPonniah Vanamoorthy
Eligibility
Inclusion criteria
Inclusion criteria: Consenting patients undergoing Elective Craniotomy surgeries, under ASA grades 1 and 2.
Exclusion criteria
Exclusion criteria: Non consenting patients Pregnant patients ASA grading 3 and above Patients with known or suspected to have allergy for study drug Emergency surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the efficacy of IV ondansetron when given alone versus combination of IV ondansetron and Oral aprepitant in management of PONV in patients undergoing elective craniotomy surgeries.Timepoint: Incidence of PONV will be recorded at initial 0 to 2 hours, at 2 to 6 hours, 6 to 24 and 24 to 48 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the incidence of PONV in patients undergoing elective craniotomy surgeries. To assess timing and need for rescue anti-emetic and/ or repeat dosing of same drug in treating PONV.Timepoint: Incidence of PONV will be recorded at initial 0 to 2 hours, at 2 to 6 hours, 6 to 24 and 24 to 48 hours postoperatively. | — |
Countries
India
Contacts
Public ContactDrVanchula Srinivasan
Kauvery Institute of Brain and Spine, Kauvery Hospital,Radial Road
Outcome results
None listed