Effects of nasal packing with Ciprofloxacin versus betamethasone versus saline in endoscopic sinus surgery.

EFFICACY OF POSTOPERATIVE CIPROFLOXACIN VERSUS BETAMETHASONE VERSUS SALINE IMPREGNATED NASAL PACKING IN ENDOSCOPIC SINUS SURGERY: AN RANDOMIZED CONTROLLED TRIAL - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/083046

Enrollment

Registered

2025-03-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified

Interventions

Intervention1: Nasal packing with Ciprofloxacin: Nasal pack soaked with Ciprofloxacin placed in the nose after functional endoscopic sinus surgery for 48 hours. Intervention2: Nasal packing with betam

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Chronic rhinosinusitis with or without polyposis Patients who offered informed written consent to undergo functional endoscopic sinus surgery. Patients from 18 years to 60 years of age.

Exclusion criteria

Exclusion criteria: Patients allergic to betametasone or ciprofloxacin Patients with Sinonasal neoplasia Patients with Glaucoma Pregnancy Patients with Bleeding disorders

Design outcomes

Primary

Measure	Time frame
Perioperative sinus endoscopic scoring by diagnostic nasal endoscopy to assess nasal mucosal healing.Timepoint: Day 2,day 7,day 28,day 42	—

Secondary

Measure	Time frame
Assessing nasal painTimepoint: Day 1 and Day 2	—

Countries

India

Contacts

Public ContactKishore khannaa A

SRM medical college hospital and research centre

sivaranjani57@gmail.com7598179875

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026