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Comparing of 2 percent diltiazem ointment and minor surgery for treating anal fissures

Effectiveness of 2 percent diltiazem topical ointment versus partial lateral internal anal sphincterotomy in management of acute fissure in ano- A randomised controlled trail. - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083034
Enrollment
70
Registered
2025-03-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K600- Acute anal fissure Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Partial lateral anal sphincterotomy (LAS): surgical procedure to treat anal fissures by making a small incision into the internal anal sphincter muscle to relieve pressure and improve

Sponsors

Aarupadai veedu medical College hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with fissure in ano aged between 18-65 years. 2. Both male and female patients are included.

Exclusion criteria

Exclusion criteria: 1. Pregnant/ Lactating women. 2. Patients with significant cardiovascular disease 3. Inflammatory bowel disease, Tuberculosis and Malignancy. 4. Previous anal surgery. 5. Associated with hemorrhoids and fistula.

Design outcomes

Primary

MeasureTime frame
To compare effectiveness of topical 2% Diltiazem ointment vs Partial Lateral internal anal sphincterotomy in treatment of patients with acute fissure in Ano.Timepoint: Study for a period of 6 weeks Assess every 2nd week I.e 2nd, 4th, 6th week.

Secondary

MeasureTime frame
To compare the time taken for the healing of fissure. To compare pain, bleeding, reccurence. Complications associated with the use of topical 2% Diltiazem ointment vs Partial Lateral internal anal sphincterotomy in treatment of patients with acute fissure in Ano.Timepoint: Study for a period of 6 weeks Assess every 2nd week I.e 2nd, 4th, 6th week

Countries

India

Contacts

Public ContactDr T Ramachandrudu

Aarupadai veedu medical College n hospital

general.surgery@avmc.edu.in9626854699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026