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Examining How Insulin-like Growth Factor Helps Bone Growth and Implant Support in patients with missing teeth

Evaluation Of The Effect Of Insulin like Growth Factor Application On Crestal Bone Level And Osseointegration Around Endosseous Implant. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082985
Enrollment
40
Registered
2025-03-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge Health Condition 2: K068- Other specified disorders of gingiva and edentulous alveolar ridge

Interventions

Intervention1: Insulin like growth factor: implants will be coated with Insulin like growth factor gel and patients will be followed up 3 and 6 months for evaluating parameters Control Intervention1:

Sponsors

Nextin Biocare Pvt Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Individuals with an age group of 25-50 years of either gender. 2. Presence of adequate horizontal(4-5mm) and vertical (12mm) dimensions of the alveolar bone based on CBCT. 3. Presence of adequate keratinized mucosa (minimum 1 mm) in the edentulous site. 4. Apparently healthy individuals. 5. Individuals with bone density classified as D2 and D3 type of bone.

Exclusion criteria

Exclusion criteria: 1. Any forms of tobacco users. 2. Individuals with parafunctional habits. 3. Pregnant and lactating women. 4. Patients taking any medication which effect healing and bone metabolism. 5. History of radiotherapy to head and neck.

Design outcomes

Primary

MeasureTime frame
to evaluate implant stability around implants coated with insulin like growth factorTimepoint: base line, 3 months and 6 months

Secondary

MeasureTime frame
to evaluate the crestal bone level around implants coated with insulin like growth factorTimepoint: baseline, 3 and 6 months

Countries

India

Contacts

Public ContactLakshmi Kanth Kolaparthy

Sibar Institute of Dental Sciences

drkanth99@yahoo.co.in9441081047

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026