Comparison of Two Blades (C-MAC Miller and Macintosh) for Intubation in Preterm Infants and Neonates

Comparison of C-MAC Miller Size 0 Blade and C-MAC Macintosh Size 0 Blade for Intubation in Preterm Infants & Neonates: A Randomised Controlled Study - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082978

Enrollment

Registered

2025-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H351- Retinopathy of prematurity

Interventions

Intervention1: C-MAC Macintosh: Intubation with C-MAC Macintosh size 0 blade in preterm infants and Neonates Control Intervention1: C-MAC Miller: Intubation with C-MAC Miller size 0 blade in preterm i

Eligibility

Inclusion criteria

Inclusion criteria: Preterm infants & neonates [from birth till 60 weeks post conceptional age (PCA) or 1 month of age].

Exclusion criteria

Exclusion criteria: 1. Neonates with known craniofacial abnormalities or congenital airway malformations. 2. History of difficult intubation. 3. Hemodynamic instability or conditions contraindicating elective intubation.

Design outcomes

Primary

Measure	Time frame
Time to Intubation (TTI): Time from insertion of the blade in the mouth to the passage of the endotracheal tube through the vocal cords.Timepoint: From the time of induction of anaesthesia till endotracheal intubation is completed. (usually 5-10 minutes from start of anaesthesia induction)	—

Secondary

Measure	Time frame
1.Time to Best Glottic View (TTGV): Time from insertion of the blade in the mouth to achieving the best possible glottic view. 2.Time to Procedure (TTP): Time from insertion of the blade in the mouth till square shaped etCO2 tracing is seen in the monitor. 3.Percentage of glottic opening (POGO) score: Graded on a scale of 0Ã¢â?¬â??100% based on visualized glottis. 4.Number of intubation attempts required. 5.Ease of blade insertion, ease of ETT insertion, ease of intubation, graded on a scale of 1 (easy) to 5 (very difficult). 6.Adverse events, including desaturation , mucosal trauma, or bradycardia . Timepoint: From the starting time of induction of anaesthesia till completion of endotracheal intubation. (usually takes 5-10 minutes from start of induction of anaesthesia)	—

Measure

Time frame

1.Time to Best Glottic View (TTGV): Time from insertion of the blade in the mouth to achieving the best possible glottic view. 2.Time to Procedure (TTP): Time from insertion of the blade in the mouth till square shaped etCO2 tracing is seen in the monitor. 3.Percentage of glottic opening (POGO) score: Graded on a scale of 0Ã¢â?¬â??100% based on visualized glottis. 4.Number of intubation attempts required. 5.Ease of blade insertion, ease of ETT insertion, ease of intubation, graded on a scale of 1 (easy) to 5 (very difficult). 6.Adverse events, including desaturation , mucosal trauma, or bradycardia . Timepoint: From the starting time of induction of anaesthesia till completion of endotracheal intubation. (usually takes 5-10 minutes from start of induction of anaesthesia)

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Countries

India

Contacts

Public ContactRenu Sinha

All India Institute of Medical Sciences, New Delhi

renusinha@aiims.edu9810305156

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026