Comparison of post operative pain relief between intravenous diclofenac with acetaminophen in combination and intravenous diclofenac alone in patients undergoing inguinal hernia surgery

An evaluation of opioid sparing effects of intravenous diclofenac - acetaminophen combination when compared to diclofenac alone in patients undergoing inguinal hernia repair - A double blinded randomised trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082847

Enrollment

Registered

2025-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Intravenous Diclofenac: At the end of surgery intravenous 75mg DICLOFENAC diluted in 10ml isotonic saline over 10min along with intravenous 100ml isotonic saline over 15min. Postoperat

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 & 2 Undergoing elective inguinal hernia surgeries under subarachnoid block

Exclusion criteria

Exclusion criteria: Patients who are not willing to participate in study ASA grade 3& 4 History of drug or alcohol abuse History of coagulation abnormalities Known hypersensitivity to any of study medication Patient on long term analgesia Patient with contraindication to spinal anesthesia Failure of spinal anesthesia

Design outcomes

Primary

Measure	Time frame
To assess the total post operative rescue analgesic(Tramadol) consumptionTimepoint: In 24 hours post operatively	—

Secondary

Measure	Time frame
1. To assess time to first request for rescue analgesia 2.To assess the post operative pain at rest and movement 3.To assess episodes of nausea, retching and vomiting 4. Overall patient satisfactionTimepoint: in 24 hours post operatively	—

Countries

India

Contacts

Public ContactDr Narla Lakshmi Bhavani Chowdary

RNT Medical College

dr_ikumari@hotmail.com9414176760

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026