Dysphagia-optimised intensity modulated radiotherapy versus standard intensity modulated radiotherapy in head and neck cancer cases. kindly note since we are comparing two advanced radiotherapy techniques, this is the simplest public title that can be added.

Dysphagia-Optimised Intensity Modulated Radiation Therapy vs Standard Intensity Modulated Radiation Therapy in post-operative cases of oral cavity carcinoma - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082834

Enrollment

Registered

2025-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Dyphagia Optimised Intensity Modulated Radiotherapy (DO-IMRT): For patients with oral cavity carcinoma, the intervention arm will be treated with Dysphagia-Optimised Intensity Modulated

Eligibility

Inclusion criteria

Inclusion criteria: Histologically proven post-operative oral cavity carcinoma. Squamous-cell carcinoma histology. Age 18-70 years of either sex. pT1-pT4, N0-3,M0. ECOG of 0-2. Adequate hematologic, renal and hepatic function.

Exclusion criteria

Exclusion criteria: Pre-existing swallowing dysfunction. Any synchronous or metachronous malignancy. Patients receiving neo-adjuvant chemotherapy. Prior chemotherapy and /or radiotherapy to head and neck region. Incomplete surgery or R2 resection

Design outcomes

Primary

Measure	Time frame
Acute ToxicityTimepoint: 3 months	—

Secondary

Measure	Time frame
Late toxicity. Disease free survival Overall survival Loco-regional control. Timepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Lahunshisha Kharbuli

Sir Sunderlal Hospital,Institute of Medical Sciences, BHU.

hmsra1801@gmail.com7704909900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026