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Effect of platelet concentrates versus probiotic augmented platelet concentrates in bone defects of teeth in stage III periodontitis patients

Effect of injectable platelet rich fibrin vs probiotic[Bifidobacterium[2x10^9CFU/G] augmented injectable platelet rich fibrin in intra osseous defects of stage III periodontitis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082828
Enrollment
28
Registered
2025-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M897- Major osseous defect

Interventions

Intervention1: Injectable platelet rich fibrin: Injectable platelet rich fibrin will be formulated from patients own blood and placed in the intraosseous defects and will be reevaluated after 6months

Sponsors

Digavinti Sushmitha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Presence of 16 natural teeth, Maxillary and mandibular molars with intraosseous defects

Exclusion criteria

Exclusion criteria: Medically compromised patients, Patients on any medications known to affect the outcomes of periodontal therapy, Insufficient platelet count, Pregnant or lactating women. Smokers or subjects using any form of tobacco Furcation involvement more than 3mm Grade II and grade III mobility

Design outcomes

Primary

MeasureTime frame
Reduction in probing pocket depth Clinical attachment level gain Radiographic bone defect fill Timepoint: Baseline, 6months—

Secondary

MeasureTime frame
Decreased Bleeding on probing Reduction in Plaque index score Timepoint: Baseline,6months—

Countries

India

Contacts

Public ContactShruthi S

Vydehi Institute of Dental Sciences and Research Centre

shruthi_s1984@yahoo.com9886824276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026