Evaluation of the impact of Prostaglandin E1 injection and Low Level Laser therapy on duration of Braces Treatment

Comparison and evaluation of the effects of Prostaglandin E1 injection with Low Level Laser therapy on Orthodontic tooth movement- An In Vivo study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082785

Enrollment

Registered

2025-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures Health Condition 2: Z768- Persons encountering health services in other specified circumstances

Interventions

Intervention1: prostaglandin e1 injection: 0.1 ml of Alpostin injection containing Prostaglandin E1 at 500mcg/ml concentration, once in 2 weeks for 80 days Control Intervention1: low level laser thera

Eligibility

Inclusion criteria

Inclusion criteria: patients with angles class 1 malocclusion and skeletal class 1 malocclusion

Exclusion criteria

Exclusion criteria: patients with class 2 and class 3 malocclusion

Design outcomes

Primary

Measure	Time frame
Accelerated orthodontic tooth movementTimepoint: Baseline, at 2 weeks, 4weeks, 6weeks, 8 weeks, 10 weeks	—

Secondary

Measure	Time frame
correction of protrusive malocclusionTimepoint: Baseline, at 2 weeks, 4weeks, 6weeks, 8 weeks, 10 weeks	—

Countries

India

Contacts

Public ContactDr Lokesh N K

RajaRajeswari Dental College and Hospitals

drlokesh8613@gmail.com9880600178

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026