Evaluation of pain after single visit root canal treatment using different temperatures and concentrations of disinfecting solution.

Evaluation Of The Effect Of Irrigation With Sodium Hypochlorite At Different Concentration And Temperature On Post Operative Pain In Mandibular Molars With Irreversible Pulpitis : A Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082769

Enrollment

Registered

2025-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Irrigation with sodium hypochlorite: Irrigation with sodium hypochlorite at different temperatures and different concentrations. Control Intervention1: irrigation With Sodium Hypochlori

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 20-60 years. Mandibular molars with irreversible pulpitis. No previous history of endodontic treatment. Non-contributory medical history.

Exclusion criteria

Exclusion criteria: Teeth with poor periodontal status. Patients with Periapical Abscess, Sinus Tracts, Intraoral Swelling, Apical Periodontitis. Re-treatment cases. Patients who have received NSAIDs or Antibiotics in three months before the study.

Design outcomes

Primary

Measure	Time frame
comparison and evaluating the effect of irrigation with sodium hypochlorite at different concentrations (1% and 3%) and temperatures (45 C and 60 C) on postoperative pain in mandibular molars with irreversible pulpitis.Timepoint: 6 hours, 12 hours, 24 hours, 48 hours , and 72 hours	—

Secondary

Measure	Time frame
a) To evaluate & compare the effect of heated 1% NaOCl at 45 C & 60 C on post operative pain in mandibular molars b)To evaluate & compare the effect of heated 3% NaOCl at 45 C & 60 C on post operative pain in mandibular molars c)To evaluate & compare the effect of heated 1% NaOCl & 3 % NaOCl on post operative pain in mandibular molars d)To evaluate & compare the effect of temperature (45 C & 60 C) of NaOCl on postoperative pain in mandibular molars. Timepoint: at every 6 hours for three days	—

Measure

Time frame

a) To evaluate & compare the effect of heated 1% NaOCl at 45 C & 60 C on post operative pain in mandibular molars b)To evaluate & compare the effect of heated 3% NaOCl at 45 C & 60 C on post operative pain in mandibular molars c)To evaluate & compare the effect of heated 1% NaOCl & 3 % NaOCl on post operative pain in mandibular molars d)To evaluate & compare the effect of temperature (45 C & 60 C) of NaOCl on postoperative pain in mandibular molars. Timepoint: at every 6 hours for three days

—

Countries

India

Contacts

Public ContactDr Ankita Sharma

Shree Guru Govind Singh Tricentanary University

Ankita_fds@sgtuniversity.org9682575180

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026