To compare BETWEEN CONVENTIONAL AND MINIMAL INVASIVE Spine SURGERY in terms of which has better outcome and also has less days of hospital stay and intraoperative blood loss and early rehabilitation

COMPARITIVE ANALYSIS OF FUNCTIONAL AND RADIOLOGICAL OUTCOMES OF OPEN TLIF (TRANSFORAMINAL LUMBAR INTERBODY FUSION) AND MIS (MINIMALLY INVASIVE) TLIF: An OPEN LABEL PARALLEL RANDOMISED CONTROLLED STUDY - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082755

Enrollment

Registered

2025-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: M431- Spondylolisthesis

Interventions

Intervention1: MIS ( MINIMALLY INVASIVE ) TLIF: - A small paramedian incision of about 3 cm would be made on the side from which cage insertion is planned. - Sequential dilators splitting the muscles

Eligibility

Inclusion criteria

Inclusion criteria: Adult with Age more than 18 years patients with single level degenerative/ lytic/ dysplastic lumbar listhesis -Meyer ding classification Grade 1 -3 with canal stenosis with or without neurodeficit with claudication/ radiculopathy with instability and not responding to conservative treatment. - Single level degenerative stenosis with claudication/ radiculopathy with congenital bony canal stenosis such that adequate decompression may entail iatrogenic instability and not responding to conservative treatment. -Willingness to participate in the study and forgo any other concomitant treatment modality with written informed consent

Exclusion criteria

Exclusion criteria: - Post traumatic spondylolisthesis -High grade (4 and above) dysplastic listhesis -Pathological fractures - Prior spinal surgeries - active infection - malignancy - Patients unfit for undergoing surgery - severe osteoporosis -Not willing to participate in the study

Design outcomes

Primary

Measure	Time frame
To compare the Functional and Radiological outcomes of Open TLIF (Transforaminal Lumbar Interbody Fusion) and MIS TLIF in adult patientTimepoint: 6 Months	—

Secondary

Measure	Time frame
To document & analyse complications, hospital stay, intraoperative blood loss in both the operative methodsTimepoint: 6 months	—

Countries

India

Contacts

Public ContactDr Priyanshu

AIIMS NAGPUR

saurabh.sah@gmail.com9423637719

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026