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Comparison between two routes of same drug administered as an additive to a local anaesthetic for Intubation in awake patient using a special device

Comparison between Nebulized and Intravenous Dexmedetomidine as an additive to Nebulized Lignocaine for Awake Fiberoptic Intubation - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082745
Enrollment
64
Registered
2025-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Awake Fiberoptic Intubation: A technique which allows a flexible oral or nasal route to provide a clear vsualisation of the vocal cords, and subsequent passage of an endotracheal tube i

Sponsors

Eras Lucknow Medical College and Hospital
Lead Sponsor
Dr Bushra Suhail
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to American Society of Anaesthesiologists physical status I or II. Patients scheduled to undergo elective surgery under general anaesthesia. Patients with predicted difficult airway (defined as mouth opening less than 3 cm or thyromental distance less than 6.5 cm or sternomental distance less than 12.5 cm or modified Mallampati class III/IV, or limited neck movements).

Exclusion criteria

Exclusion criteria: Patients with known or suspected allergy to Dexmedetomidine or Lignocaine. Patients with thrombocytopenia or bleeding diathesis. Patients with psychiatric disorder or uncooperative patients. HR less than 50 bpm. Second or third degree heart block. Pregnancy and lactation.

Design outcomes

Primary

MeasureTime frame
To assess the total duration required for awake fiberoptic intubation. Timepoint: Less than 15 mins

Secondary

MeasureTime frame
1 To assess the patient comfort and tolerance during intubation using patient tolerance score (PTS). 2 To assess the degree of sedation using Ramsay sedation score (RSS). 3 To assess the intensity of cough during the procedure using cough score. 4 To assess the variations in heart rate (HR), mean arterial pressure (MAP), Oxygen saturation (SPO2) at different time intervals. Timepoint: At the time of intubation 5 mins after intubation and 10 mins after intubation

Countries

India

Contacts

Public ContactDr Bushra Suhail

Eras Lucknow Medical College and Hospital

docraj198810@gmail.com8299081739

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026