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Comparison two drugs (Nalbuphine vs Tramadol) for post surgery pain relief

Comparison Of Intravenous Nalbuphine Versus Intravenous Tramadol For Postoperative Analgesia In Patients Undergoing Elective Laparoscopic Surgeries-A Randomised Blinded Trial - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082737
Enrollment
62
Registered
2025-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: K358- Other and unspecified acute appendicitis Health Condition 3: K358- Other and unspecified acute appendicitis Health Condition 4: K409- Unilateral inguinal hernia, without obstruction or gangrene Health Condition 5: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: NALBUPHINE: Nalbuphine is synthetic opioid of phenanthrane series, It is partial agonist at kappa-opioid receptor(Providing Analgesia) Intervention2: Tramadol: Tramadol is synthetic opi

Sponsors

Narayana Hrudayalaya Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaethesiologist grade 1& 2

Exclusion criteria

Exclusion criteria: 1.Antipsychotic drugs 2.Drug allergy 3.Opioid use within last 3 months 4.Seizure disorder 5.Anticipation of difficult airway 6.Renal & Liver dysfunction 7.Substance abuse 8.Psychotic disorders

Design outcomes

Primary

MeasureTime frame
Mean duration for first rescue analgesic between Nalbuphine vs TramadolTimepoint: When VAS score reaches 3/10 in the postoperative period

Secondary

MeasureTime frame
Ramsay sedation scoreTimepoint: 1st 8 hours of postoperative period;VAS score between the two groupsTimepoint: 1st 8 hours of postoperative period;Nausea, vomiting, respiratory depressionTimepoint: 1st 8 hours of postoperative period

Countries

India

Contacts

Public ContactDr Monisha J

Narayana Hrudayalaya Hospital

indumathi.t.dr01@narayanahealth.org

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026