Effectiveness of lignocaine jelly versus betamethasone gel on endotracheal tubes in reducing postoperative sore throat,cough and hoarseness of voice.

Comparison between lignocaine jelly versus betamethasone gel applied over endotracheal tube to reduce postoperative sore throat,cough and hoarseness of voice. - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082734

Enrollment

Registered

2025-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 0.05% betamethasone gel: Dose- 0.05% betamethasone gel 1-2ml, as a lubricant applied over endotracheal tube cuff once before intubation. Control Intervention1: 2% lignocaine jelly: Dos

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I, II, III 2. Elective procedures requiring endotracheal intubation

Exclusion criteria

Exclusion criteria: 1. ASA grade IV & V 2. Patient with history of adverse drug reaction to study medications 3. Pregnant and lactating women 4. Patients having upper respiratory tract infections and oronasal surgeries 5. Anticipated difficult airway 6. Vocal cord pathology

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative sore throat, cough and hoarseness of voice after endotracheal intubation.Timepoint: Immediately after extubation, 1 hours,4 hours, 6 hours,12 hours, 24 hours, 36 hours, and 48 hours.	—

Secondary

Measure	Time frame
To see the hemodynamic responseTimepoint: For 2 hours	—

Countries

India

Contacts

Public ContactDr Reema Vansola

BJ Medical college Ahmedabad

reema.vansola@gmail.com9099952630

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026