Comparison of 0.75% ropivacaine intra tracheal and intra cuff in general anaesthesia for post operative sore throat and cough

Comparison of intra-cuff ropivacaine versus intratracheal ropivacaine on the hemodynamic response to endotracheal tube during emergence from general anesthesia: A randomized controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082730

Enrollment

Registered

2025-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: General anaesthesia: Group A- Patient will be given general anaesthesia, before endotracheal intubation with endotracheal tube, using atomizer 0.75% ropivacaine 2ml -3ml will be sprayed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient undergoing various elective surgeries under general anaesthesia. 2. Age between 18-65 years old 3. American Society of Anaesthesiologists (ASA) I & II.

Exclusion criteria

Exclusion criteria: 1.Patients known allergic to the local anaesthetic drugs. 2.Patients undergoing emergency procedures. 3. Haemodynamically unstable patients & pregnant patients. 4. Patients with pre-existing sore throat, hoarseness, cough, recent respiratory illness or history of airway hyperactivity 5. Patients with a difficult airway where the anticipated duration of laryngoscopy exceeds 15 seconds. 6. Patients with a history of cardiac, liver or renal diseases.

Design outcomes

Primary

Measure	Time frame
HR,BP will be rising during the time of extubation, which will be blunted in this study. Post operative sore throat and cough will not be there.Timepoint: During extubation to immediated post operative period upto 2 hours	—

Secondary

Measure	Time frame
To compare the effect of intra-cuff ropivacaine (0.75%) versus intratracheal instillation of ropivacaine (0.75%) using atomizer on post operative sore throat and cough.Timepoint: Immediate post operative period	—

Countries

India

Contacts

Public ContactDR Kathija Begam A

Jawaharlal Nehru Medical College

dr.raghavendra.kalal@gmail.com9880712568

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026