Health Condition 1: K859- Acute pancreatitis, unspecified
Conditions
Interventions
Intervention1: Goal directed fluid therapy: Eligible adults admitted with new onset of acute pancreatitis will be enrolled and randomized into Group A GDFT(Goal directed fluid therapy) as intervention
Sponsors
MGM Medical College and Hospital Aurangabad Maharashtra
Eligibility
Inclusion criteria
Inclusion criteria: All patients admitted to MGM medical hospital Aurangabad Maharashtra , with Acute pancreatitis international consensus criteria VII (any 2 of 3) 1)classical pain in abdomen (acute onset of severe epigastric pain ,generally radiating to back) 2) Increase in serum amylase and lipase levels higher than three times the upper limit of normality 3)Signs of Acute pancreatitis on imaging (C T or USG)
Exclusion criteria
Exclusion criteria: 1)Chronic pancreatitis in which acute exacerbation cannot be confirmed. 2)History of any fluid overload diseases like cardiac failure ,abdominal hypertension ,pleural effusion in the past three months . 3)Unable to provide informed and written consents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the effectiveness of goal directed fluid therapy in management of acute pancreatitis.Timepoint: Baseline(0) 4 hours 8 hours 12 hours 16 hours 20 hours 24 hours 28 hours 32hours 36 hours 40hr 44hours and 48hours with follow up post 48hour period until the end of 1st month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To study an assessment of feasibility of trial in India 2)To calculate optimal fluid requirement in management of pancreatitis 3) To study the effectiveness of GDFT in decreasing complications of acute pancreatitis 4) to study cost effectiveness of GDFT by reducing icu stayTimepoint: One month follow up | — |
Countries
India
Contacts
Public ContactDR VIKAS DESHMUKH
MGM MEDICAL COLLEGE AND HOSPITAL AURANGABAD
Outcome results
None listed