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Platelet application to gums to treat gum diseases

Clinical efficacy of subgingival application of injectable platelet rich fibrin as an adjuntive therapy to scaling and root planing - A split mouth randomized clinical trial - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082640
Enrollment
40
Registered
2025-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: injectable platelet rich fibrin: IPRF applied subgingivally after scaling and root planing- Locally applied into the periodontal pocket and patient will be recalled after 14days,1month

Sponsors

Sri Hasanamba Dental College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. willingness to comply with study protocol 2. subjects diagnosed with chronic generalised periodontis 3. subjects should have mild to moderate periodontal pockets 4. subjects age group 25-55years

Exclusion criteria

Exclusion criteria: 1.Subjects suffering from any known systemic diseases. 2.Subjects who had received any antibiotic therapy in the last 6 months. 3.Pregnant and lactating women. 4.Subjects who are smokers. 5.Subjects who had received any chemotherapeutic mouth rinses or oral irrigation or using any other oral care products during the past 3 months.

Design outcomes

Primary

MeasureTime frame
Reduction of clinical signs, Gingival index, Papillary bleeding index, Probing pocket depth, Clinical attachment levelTimepoint: Reduction of clinical signs, Gingival index, Papillary bleeding index, Probing pocket depth, Clinical attachment level will be assessed at baseline,14th day,1month,3month

Secondary

MeasureTime frame
Reduction of clinical signs, Gingival index, Papillary bleeding index, Clinical attachment levelTimepoint: 3 months

Countries

India

Contacts

Public ContactDR V VAISHNAVI

Sri Hasanamba Dental College and Hospital

vivekcodsperio@ymail.com9980843531

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026