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Co- relating MMP-8 values and periodontal inflamed surface area in patients with periodontitis before and after scaling and root planing

Estimation of salivary matrix metalloproteinases- 8 (MMP-8) and its correlation to periodontal inflamed surface(PISA) before and after non- surgical periodontal therapy - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082598
Enrollment
42
Registered
2025-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non surgical periodontal therapy: Chronic periodontitis patients will undergo full mouth ultrasonic scaling and root planing Control Intervention1: NIL: NIL Control Intervention2: NIL:

Sponsors

Shalini Kumari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with a minimum of 20 teeth. Patients with no history of periodontal therapy in the last 6 months. Subjects with no history of any kind of systemic diseases.

Exclusion criteria

Exclusion criteria: Patients with history of smoking and tobacco chewing Pregnant or lactating women. Patients on any kind of medications.

Design outcomes

Primary

MeasureTime frame
to estimate salivary MMP-8 to PISA in individuals with healthy periodontium and periodontitis before and after non-surgical periodontal therapyTimepoint: salivary MMP-8 and PISA values will be calculated at baseline and non surgical periodontal therapy will be carried out at baseline. After 3 months salivary MMP-8 and PISA will be calculated.—

Secondary

MeasureTime frame
Not applicableTimepoint: Not applicable—

Countries

India

Contacts

Public ContactShalini Kumari

KLE Academy of Higher Education and Research

menakakaralwad@gmail.com08073231684

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026