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Effectiveness of DFDBA with A-PRF vs ADG with A-PRF in Socket Preservation: A Comparative Study

Comparative Clinical, Radiographic & Histological Evaluation of Demineralized Freeze-Dried Bone Allograft (DFDBA) and Autologous Dentin Graft (ADG) with Advanced Platelet Rich Fibrin (A-PRF) in Alveolar Socket Preservation. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/082589
Enrollment
18
Registered
2025-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K08- Other disorders of teeth and supporting structures

Interventions

Intervention1: Test Group- Autologous dentin graft with A-PRF: Intervention- ADG + A-PRF in test group immediately after extraction Control Intervention1: Control group- Demineralized Freeze-Dried Bon

Sponsors

Sharad Pawar Dental College Sawangi Meghe Wardha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients indicated for implant following extraction. Because of reasons like, fracture of root, failure of endodontic treatment, resorption (internal and external), over-retained primary teeth, non-restorable carious lesions, residual roots. 2) A complete mouth plaque score of less than 25% indicates good oral hygiene. 3) Existence of a natural tooth in opposition 4) Adjacent teeth presence 5) Thick gingival biotype 6) The clinical and radiological appearance of the unbroken alveolar bone walls 7) 4 mm of bone radiographically at root apex. 8) D-1, D-2 or D-3 bone quality.

Exclusion criteria

Exclusion criteria: 1) Patients with impaired systemic health that would interfere with the process involved with repair and healing of bones e.g. (Diabetes mellitus, Osteoporosis, Blood disorders). 2) Significant differences in maxilla-mandibular space. 3) Presence of para functional habits such as bruxism or clenching. 4) Presence of proclined teeth, teeth with interdental spacing, rotated or mal-aligned anterior teeth. 5) History of alcoholism, excessive smoking or drug abuse. 6) D-4 bone quality. 7) Radiotherapy and chemotherapy history. 8) Debilitating temporomandibular joint pathosis. 9) Untreated dental diseases. 10) Pregnant and lactating mothers.

Design outcomes

Primary

MeasureTime frame
Radiographic analysis, we will access new bone formation, change in sockets vertical alveolar boneTimepoint: Post operatively four months

Secondary

MeasureTime frame
The main results are linear phenotypic dimensional changes at baseline & four months after healing at two locations in the mid-facial & mid-palatal bone & soft tissue thicknessTimepoint: Post operatively four months

Countries

India

Contacts

Public ContactMahima Ravindra Kothekar

Sharad Pawar Dental College, Sawangi (Meghe)

pavbajaj@gmail.com8412045019

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026