Effect of Ayurveda treatment in the Management of Hrudroga(Coronary Artery Disease)

RANDOMIZED CLINICAL TRIAL TO EVALUATE THE EFFICACY OF GOMUTRA HARITAKI RASAYANA WITH AND WITHOUT VIRECHANA KARMA IN THE MANAGEMENT OF KAPHAJ HRUDROGA [CORONARY ARTERY DISEASE] - Ayurveda treatment in managment of Hrudroga (Coronary Artery Disease)

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082579

Enrollment

Registered

2025-03-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I779- Disorder of arteries and arterioles, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Both Male and Female. Age group 20-65 years. Class I, II and IIa(III) as per Canadian Cardiovascular Society grading of angina pectoris. CAC Scoring less than 400 or less than 90 percentile. Brain Natriuritric Peptide than 400pg/ml Those are able to give written consent ECG- T wave inverted without Q wave / ST elevation. Stress TMT- Positive. Troponin T test- Negative. Angiography less than 60% occlusion in any of the coronary artery.

Exclusion criteria

Exclusion criteria: Age group greater than 65 year Renal insufficiency (S.Creatinine greater than 2 mg/dl, Blood Urea greater than 40 mg/dl) ECG finding S/O ST Elevation LBBB Q wave 2D ECHO showing presence of any valvular heart disease. Tachycardia or Ventricular arrhythmia Low Left Ventricular Ejection Fraction (LVEFless than 40%). Positive Troponin Test. CT Angiography lesion graeter than 60%. CPK-MB greater than 5%. Prolonged or traumatic cardiovascular resuscitation. Previous Coronary Intervention (within 6-12 months) or any bypass surgery. Prolonged chest pain (greater than 30 mints) associated with vomiting and syncope Chest pain with vagotonia (bradycardia, pallor and syncope) Recorded Blood Pressure graeter than 180/100mmHg Raised Prothombin time, Activated Partial Thromboplastin Time. Heart failure (Brain Natriuritric Peptide grater than 2 times) BMI less than 25.

Design outcomes

Primary

Measure	Time frame
Change in volume and percentage occlusion of soft and hard plaques in CCT angiographyTimepoint: baseline and at 12 weeks	—

Secondary

Measure	Time frame
Change in coronary artery calcium scoring. Change in stress TMT. Change in Chest Pain/ Discomfort Questionnaires. SF-36 BODE Index. Timepoint: baseline & at 12 weeks	—

Countries

India

Contacts

Public ContactDr Divya Kajaria

ALL INDIA INSTITUTE OF AYURVEDA

divyakajaria@gmail.com8826167515

Outcome results