Comparative study of two different doses of dexmedetomidine for producing programmed hypotension during Functional endoscopic sinus surgery

A comparative evaluation of two different doses of Dexmedetomidine in producing controlled hypotension during Functional endoscopic sinus surgery - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082570

Enrollment

Registered

2025-03-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J014- Acute pansinusitis Health Condition 2: J010- Acute maxillary sinusitis

Interventions

Intervention1: Two different doses of dexmedetomidine for controlled hypotension in FESS: Patient will induced by propofol( 2-3 mg/kg ) followed by succinyl choline (1.2 to 1.5 mg /kg body weight). L

Eligibility

Inclusion criteria

Inclusion criteria: Patients of all sex Elective FESS surgeries aged from 18 years to 50 years. Patients with ASA Grade I and II physical status

Exclusion criteria

Exclusion criteria: • Patient refusal • Pregnancy • Any known allergic condition or contraindication to GA, • Hypertensive patient undergoing antihypertensive medication • Any cardio vascular, renal disease

Design outcomes

Primary

Measure	Time frame
to evaluate and compare the following factor in two different dose group for dexmedetomidine- 1.mean arterial pressure 2. heart rate variability 3. bleeding 4. time taken to induce hypotensionTimepoint: Time taken to induce hypotension	—

Secondary

Measure	Time frame
amount of bleedingTimepoint: intraoperative	—

Countries

India

Contacts

Public ContactDR SUNEETA DUTTA

Silchar medical college and Hospital

drsuneetadutta@gmail.com9435074110

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026