Evaluating the capacity of probiotic chewable tablets containing probiotic bacteria on halitosis enzyme levels in patients with bad breath as an adjunct totooth cleaning â??a randomized control trial study.

Evaluating the efficacy of probiotic chewable tablets containing lactobacillus reuteri on salivary beta-glucosidase levels in patients with oral malodour as an adjunct to scaling and root planing,a randomized control trial study. - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/03/082544

Enrollment

Registered

2025-03-18

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K055- Other periodontal diseases

Interventions

Intervention1: Probiotic tablet containing lactobacillus reuteri: Probiotic chewable tablet containing lactobacillus reuteri to be given to half of the sample population along with scaling and root pl

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age group 25â??60 years 2.Both male and female patients 3.Subjective feeling of bad breath. 4.Atleast 16 teeth should be present with a minimum of 4 teeth in each quadrant. 5.Systemically healthy individuals. 6.Who are willing to participate and have signed written consent.

Exclusion criteria

Exclusion criteria: 1.Presence of any systemic conditions or debilitating diseases. 2.Smokers, alcoholics, pregnant or lactating women. 3.A recent history or presence of any acute or chronic infections. 4.Patients who had undergone periodontal therapy in the last 6 months. 5.Patients who are paan/tobacco/betel nut users. 6.Patients who are physically or mentally challenged. 7.Patients with periodontal disease or rampant decay with excessive open carious lesions. 8.Patients with Xerostomia.

Design outcomes

Primary

Measure	Time frame
Salivary beta GlucosidaseTimepoint: At Baseline,1 Month and 3 Months	—

Secondary

Measure	Time frame
salivary beta glucosidase level decreased in probiotic supplementation.Timepoint: 3 months	—

Countries

India

Contacts

Public ContactLAKSHMI C

EDUCARE INSTITUTE OF DENTAL SCIENCES

srk.puthalath@gmail.com9995693673

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026